Unless you've got a 38 Super made before the 1970's there's no need to slug the barrel. It'll be set up for .355 (9mm) bullets. Back in the IPSC heydays guys would even go so far as to use the really heavy .357 bullets to make major. I wouldn't do it though. They were for race guns, and they did take beatings doing stuff like that. No need to make major these days . . .
I've had a lot of success with No 5 and 124 gr bullets for light rounds on the range. I've used No 7 in both 124 and 147 gr bullets at higher velocities. If I want stompin' full house, 3N37 is about the best around. Burns very clean, and very consistent velocities.
Somewhere around here I listed all that stuff . . .