Many variables involved. I started back in the 1960s with Lee Classic Loaders for about 10 bucks for each caliber, Lee still makes them for around $20.00 if shopped for right. Slow, but they produce very good ammo.
I currently have two older Dillons, cast my own boolits for both rifle and pistol, lots of powders and primers bought back in the days of cheap. I can handload most pistol calibers for less than 5 cents a round, rifle calibers for just a bit more.
With that said, dependent upon your needs or desires, today your mechanical reloading equipment can run from a few bucks, into the thousands.
New brass is expensive if purchased, (me, I pick up any and all reloadable brass) primers will run around $40.00 a thousand, powder about $20.00 +/- a pound. Condom bullets are expensive, shoot as cast boolits, (Lee makes low priced molds) much, much, less so, if one wants more precision cast boolits, bit more expense involved for mechanical equipment.
Something to bear in mind, there are 7,000 grains in a pound. If you reload say for a .38 Special, using 3.5 grains of Bullseye powder, that is 2,000 rounds from a pound of powder. For .45 acp, 3.8 to 4.2 grains of bullseye works great for me.