I've got a Ruger 10/22 converted to 22 short that has accounted for multiple varmints here on the farm. Actually, it has dispatched more anmals than my hi powered. Big bore hunting guns.
Sorry, but I don't understand why someone would convert a 10-22 to the .22 short. Pumps, lever-actions, even bolt-actions can handle shorts and might function better. Standard velocity ammo LR ammo in a 10-22 might even be a better solution than .22 shorts. Also, unless the barrel is chambered for shorts, an eroded ring may eventually form that will make shooting long/long rifles fail to extract. It will probably take a lot linger than in my old Rem 514, due to improved steel, but it can happen.
Regardless, you pay your money and you take your choices.