Thats when you change to Federal primers.
If the proposed use for a handgun is some kind of competition, and the user used his/her own handloads, this remark might make some sense.
But otherwise it doesn't, and I'm not aware of many "gun-games" where a Smith & Wesson model 66 is the favored choice.
I, and most others, have absolutely no use for a handgun that has an action that's so light it's dependent on a particular brand of primers - or any other component.
What, for whatever reason, that one brand isn't available? Or the manufacturer changes their specifications? Or a mainspring takes just enough set so that ignition falls off the knife-edge toward the unreliable side?
Last but not least, a hangfire can leave you with ruined gun if a squip leaves a bullet stuck in the bore, and is followed by a fast "next one."
For most uses, a trigger pull that
feels too good to be true, probably is...