If we're getting into historical anecdotes, I have one too.
I just reread a book about Norwegian SIS agents during WWII. That is, soldiers from the free Norwegian forces who were seconded to the British Secret Intelligence Service and sent to occupied Norway with short wave radios.
Anyway, one of them was triangulated (as they routinely were) and before he had time to pack up and leave, he saw a line of German troops and Gestapo approaching him while searching the mountainside where he had hidden his transmitter. He had no less than five sub-machineguns in his cave (probably Stens and/or Thompsons, the book doesn't say), but he thought he needed more range so he grabbed a .22 with a peep sight. He evaded all but one of the 300 pursuers. He came face to face with a soldier armed with a Schmeisser, both took cover and exchanged several shots before the German lost. The agent got away by swimming to the next island. In april, right on the Arctic circle.
These agents were the real thing, what Ian Fleming based his somewhat less real James Bond on.
Taking big game with a .22: Humanely or not, it was not uncommon to harvest moose with .22s during the WWII occupation of Norway. The hunters may have had other rifles available, but when there is a death penalty for you and possible concentration camp for your family if you're caught with a gun, I guess noise is an important consideration. Although the occupants were not overly eager to investigate anything that happened in the forest, the investigators had a tendency to disappear...
If I for some reason had to head for them thar hills, my first choice for a long arm would most probably be my CZ 452 and muzzle can. I'd probably stick a short gun in my pocket too, in a surival situation maybe my single action .44 since there are lots of moose in "my" hills. But I don't have any detailed plans for "what to do when the comet strikes", so I would probably waste several seconds in front of the gun safe making up my mind...