In my experience, 4064 is pretty temperature sensitive. I live in N Alabama and we see temps of 100 in the summer to a few mid teen days in the winter. My 308 load is a 165 SP Gameking on top of 45grains of IMR 4064 using Hornady brass and standard LR CCI primers. If I am zeroed at 100 yards in the middle of summer, I find the groups drop exactly 2" when the weather gets below 45 degrees. It's really not that big of a deal, but I still want a powder that will shoot the same year-round. 4064 Does't measure to well through my powder dispenser either.