Depends what sort of pocket.
Pants pockets, no. Too big. The slide is rather more slender than any Glock, but it's stil a bit too big.
Coat pocket, it depends. If you're talking about a down parka where the handwarmer pocket is inside the cells of down, which will keep it from printing, then yes. I sometimes have mine in a Desantis nemesis in the right handwarmer pocket of such a parka, with the pocket snapped closed as additional retention.
Also good in some thick wool overcoats, if the inside breast pocket has a wide enough opening.