I'm going to stick my neck out, because I haven't checked this out to be sure.
But the 2nd. generation Colt's were made using semi-finished castings purchased from Uberti. Therefore I would presume that a conversion cylinder for a Uberti would work in the Colt.
I suggest that you check with the cylinder manufacturer.
Another thing that hasn't been brought up should be. As a rule of thumb, the bore (groove) diameter on these cap & ball revolvers is way oversized for the .452" bullets used these days in .45 Colt ammunition. This won't cause a safety problem, but it may have negative effects on accuracy. Some shooters may not be able to tell the difference, or perhaps don't care - but I'm not one of them. Those revolvers made by the main Italian makers as cartridge revolvers in the first place do have barrels that correctly match the respective cartridges' bullet diameter, but they are not intended to be backward converted to c & b.
But the 2nd. generation Colt's were made using semi-finished castings purchased from Uberti. Therefore I would presume that a conversion cylinder for a Uberti would work in the Colt.
I suggest that you check with the cylinder manufacturer.
Another thing that hasn't been brought up should be. As a rule of thumb, the bore (groove) diameter on these cap & ball revolvers is way oversized for the .452" bullets used these days in .45 Colt ammunition. This won't cause a safety problem, but it may have negative effects on accuracy. Some shooters may not be able to tell the difference, or perhaps don't care - but I'm not one of them. Those revolvers made by the main Italian makers as cartridge revolvers in the first place do have barrels that correctly match the respective cartridges' bullet diameter, but they are not intended to be backward converted to c & b.