Yes, I was going to mention that: the grip type that seems to soak up monster recoil the best is the Ruger Bisley type (which is really based more on a custom gun called the "#5" than the old Colt Bisley).
Two ways to get there: get a Ruger Bisley in 44Mag or 45LC (similar power level) and either shoot that horsepower level, and/or upgrade it later with a chamber/caliber conversion to something wild, OR you could get a BFR in any caliber, and convert that to Bisley for about $200 - $250 if you do it yourself.
See, the BFRs are based closely enough to the Ruger design that a lot of parts are compatible, including grip frames, hammer and trigger. So you could homebrew a "Bisley BFR"
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Here's a whole thread containing Ruger SA upgrade bits, including a complete "Bisleyize your Ruger/BFR kit":
http://www.thefiringline.com/forums/showthread.php?s=&threadid=80872
If you're going to start with a factory Ruger, a VERY good specimen is this variant:
http://www.ruger-firearms.com/Firearms/FAProdView?model=862&return=Y
That's the Ruger "Hunter Model", heavy barrel, scope rings and mounts included, and already "converted to Bisley". In "Bisley flavor", it's brand new this year.
This is the non-Bisley version:
http://www.ruger-firearms.com/Firearms/FAProdView?model=864&return=Y
These are about $600, often discounted less. Very good guns, with the Bisleyoid being the best - I strongly recommend handling a Ruger Bisley and see if it fits your hand though, as the grip is a little weird. Really soaks up the big boomers though!
Caliber conversions are available from several gunsmiths for about $400 for a basic job, more if you want it line-bored for extreme accuracy. With line-boring, you'll be into it for more than you'd pay for a BFR but you're liable to get better accuracy in a caliber like 454Casull or 475Linebaugh.
So, you could start with a 44Mag Bisley Hunter, recoil with a 53oz gun with that superb grip will tame the 44Mag down, you can start with 44Spl or light 44Mags and work your way up to monster hunting loads, and when you really want to go past the 44Mag, off to a gunsmith
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