Depending on whether you use cast or jacketed bullets, a 50rnd box could run you anywhere from about $8 to $15 to reload. The price of lead has gone through the roof recently. Cast bullets being much cheaper than the jacketed. This is of course assuming that you re-use your brass at least 10 to 15 times, which is easily done. I've loaded .44mag full power loads up to 20 times in the same brass with no failures of any kind. I haven't gone past 20 reloads yet just to be safe, but the brass can certainly take it. If you cast your own it's even cheaper. I can reload a 50rnd box of .44mag for about $4, but I cast my own for those. They type of powder makes some difference. Faster powders are cheaper because you don't use as much, but they usually don't produce higher velocities either. It just depends on what you want to do.