What is the best centerfire varmint cartridge?

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viking499

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I know this is a wide open question and I will get a variety of responses.......

But, what do you think is the best centerfire varmint cartridge? Say for critters under 40-50 lbs and at distances from 0-400 yards.

What is your regular or standby cartridge, critter and average yardage (not longest shot). And it can be more than one choice.
 
Hard to beat 22 250. Lots of rifle calibers will work well with minimum recoil. If I hunted in a lot of wind I might go with a 30 caliber round.
 
22-250. I've shot many, many yotes with everything from 22 mag to .243 but a 22-250 is hard to beat. 204 Ruger is best for foxes, coons, and such and not too shabby on yotes, so I'd say it is a close second.
 
For 400 yards, the .22-250 and the .220 Swift are a bit better than the .223. There are a couple of other uber-fast .22s out there, but much less popular and are rarely mentioned. One is a Weatherby...

I like the .223, but I basically regard it as a 300-yard cartridge, insofar as reliable hits and clean kills.
 
A lot of guys use .223, but out here in the west, we see a lot of coyotes mousing in hay fields. No cove,r so long shots to 500 yards. I like my .22/250 for that reason. I know almost all of the called in yotes are within 100 yards and a lot of calibers will do. But all around, I want my .22/250. I have used one for around 35 years.
 
50 pound critters at 400 yards?
Makes me wonder why the 6mm Rem isn't far more popular than it is..

As far as .22 centerfires go, .22/250 & .220 Swift are head and shoulders above .223 at 400 yards, and even if you have your .223 trajectory down pat, they still are on heavier vermin.
 
What Art said. Out to and including 300 yards, the .223 is just fine for everything from woodchucks to coyotes. Past 300, you need a bit more velocity to get reliable bullet performance. I think this is where the .243 and .22-250 really come into their own.
 
25WSSM 75gr V-Max zipping along at 3722 FPS






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Depends on the rifle. I have seen prairie dogs exploded at 1012 yards with a .223. Can't believe I just praised that round. But I did see it. And I have seen prairie dogs explode at 1043 yards with a 22-250. But both guns were complete customs (hand built by the owner) and shooting carefully worked handloads. My vote goes for 6mm, .243, or 22-250.
 
The .223 for 300 yards and under, and A .243 Win. For longer shots or windy conditions. I like the .223 with 40 gr bullets at 3700 fps, and the .243 Win. With 70 gr bullets st 3400 fps.
 
.25-06. Big enough for antelope with a soft point, or with a hollow point or ballistic tip it's doom on varmints.

It's a far more flexible round than .223, with bullets up to say 120 grains. Downside is a long action and a typically heavy rifle to get the best accuracy. Plus side is they are still sold in standard sporter weight barrels.
 
I'm with Dr.Rob as I've used the .25-06 for 37 years. In fact it was the only centerfire rifle I owned for 20 years.

But I'd have no problem using .22-250 or .243 for that matter.
 
savannas dad. You have some pretty large velocity deviations. Hopefully these weren't all loaded to the same level.
 
I have used my 458 Win Mag from time to time but otherwise 22-250 is the prairie dog killin champ :scrutiny:
 
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