Gaiudo,
Take this with a grain or six of salt, because even though I own .357 mag in revolver (mod 65) and carbine (1894C), I've not shot a .44 mag.
But I understand from accounts that the .44 mag in handgun is more of a handful than the .357 mag. The latter, for me (a smaller person), now, is enough. Hot rnds are not always fun, but are controllable. I can get a double tap easy enough. I'm not sure I could do the same with .44 mag. .44 mag in a carbine? Piece of cake. But not so in a revolver, me thinks. I'm more interested in controllability for that second shot than in the damage that could be done with the first. But that's just me. YMMV.
Plus, for me, where I live, for what I need a gun to do, .357 mag is plenty. I'm not faced with grizz here, or 400# monsters. Only black bear and large two-legged predators. I'm happy with .357 mag. It'll do a number on deer at reasonable ranges as well.
Should I go north, say to N Idaho or further, I'd consider .44 mag combo.
Nem