I've tried a bunch of different powders for 300 WM, my favorites, and especially for larger game such as elk has been IMR-7828 or RL22 and a 165 gr. Speer Hot Core. I've yet to have anything but a good clean kill happen with this combination.
But there are a bunch of really great powders that will drive a well constructed 165 gr. at typical 300 Win. mag. authority. H1000, RL22, IMR-4831, IMR-4350, my goodness, the list goes on and on.
I've been hooked on the Speer Hot Core for almost 3 decades, so that will be my single recommendation for a good elk projectile. I've also been very pleased with it on all other big game, including deer, antelope, bear. But one particular characteristic to be aware of, is it doesn't do well at lower velocities, it needs good velocity of 3000+ fps..
GS