I carry my 1911 with the thumb safety engaged. My other handguns are DAO autos, or revolvers, without safety levers. I learned handgunning with a 1911, and have never forgotten to engage the 1911 thumb safety as necessary.
I can only speculate whether I would reflexively engage a 1911 thumb safety, had I started with a different weapon system; I can be fairly clumsy and absent-minded. Notably, I did not carry a 1911 from mid-2002 to early 2012, just DA handguns and Glocks, but as soon as I tried the 1911 again, all was well with safety manipulation, immediately, for which I am grateful.
I did try a Third-Generation S&W auto, the 3913, in the 1990s, which has a safety lever that operates in the reverse direction, compared to a 1911, and while I never forgot the safety, I worried about it, and soon sold the 3913. I could carry it off-safe, but worried about actually thumbing it down while drawing, which would actually put it on safe when I needed it to fire.