Or for that matter,
any other gun normally used for big game hunting. The first deer I ever shot, a doe mule deer, ran about 40 yards
uphill after I shot her in the ribs with my .308 Winchester. Then she stopped in the middle of the old logging road I'd been walking. I was only 14 years old, and I thought I'd missed because all the old guys I knew (including my dad) had told me a .308 would "knock em down."
So I shot her again in the ribs. And again. And again. And again. As I was trying to shove a fresh magazine in my Model 100 Winchester, the doe collapsed in her tracks.
You could cover all five bullet holes on the one side of that doe's ribs with one hand. There was nothing left of her heart, and not much left of her rib cage on the other side.
Anyway, due to that experience over 50 years ago, I learned the myth of "knock down power" is just that - a myth. And about 10 years after that I had to stifle a laugh when another old guy told me a wounded deer will always run downhill.
Disclaimer - OK, sure - I've shot deer, elk and antelope that
appeared to be "knocked down" when they were hit. I've even seen a few of them jump right back up, and
sometimes they ran downhill after they're hit. But neither "knock down" nor "run downhill" is a sure thing.
Edited to include - I've shot 3 mule deer with my beloved .308 Norma since I got it. Each of them appeared to be knocked right off their feet when they were hit, and not a one of them got back up.
Therefore, because I'm an "old guy" of 69 now, I'm qualified to tell young hunters that a .308 Winchester won't always "knock deer down." but a .308 Norma Magnum
will.