With a proper grip its impossible to hold the CZ correctly without deactivating the safety, same as a 1911.
I own several Colt 1911s. Right now I'm holding a Combat Commander w/ambi safety. Safety on or safety off. The grip is the same. You're mistaken re the 1911.
The only CZ I own is a rifle, but I suspect you're mistaken about the CZ handgun as well.
To the OP. Again, if you've been carrying a DA revolver all those years, that's what your brain is programmed for. In a high stress situation, you (the average citizen who does not constantly train re various scenarios) lose the ability to "reason" and "think logically." The average citizen in an instantaneous crisis tends to panic. You'll do exactly that which you've programmed yourself to do. You'll repeat your training.
So let's say you've carried a revolver and that's how you trained. Your brain is conditioned that, should the need arise, you simply draw the weapon and pull the trigger and the bullets fly.
Then you start carrying a 1911 with an external safety, and you carry it cocked and locked. (That's a round in the chamber, the hammer cocked and external safety engaged.) You suddenly find yourself in a critical situation where your life is in danger.
You panic. You draw your weapon and stand there and are trying to pull the trigger, but nothing happens. That's because in a state of panic you've forgotten that, unlike the revolver, you've got to
disengage the manual safety.
And anybody who says this can't happen, does not know what they're talking about.
I remember an actual event involving a police officer who, throughout his live fire training, was required to police his brass. They used revolvers, and after they fired a cylinder of shells, were required to pick up the brass before they reloaded.
This officer got involved in a shootout. He emptied his revolver and ejected the cases. The bad guy rushed him around a corner and the police officer was on the ground, picking up his spent cases. The bad guy killed him.
Choose whatever weapon you want. Just make sure that you train with it so much that, your brain knows, no matter the situation, to 1) draw weapon, 2) disengage the manual safety, 3) pull trigger, etc.
Good luck.