I, personally, having heard many horror stories about mangled sideplates, and teeny tiny parts launching themselves into the air, never to be seen again, have foregone removing any of my sideplates. This has been a struggle at times, but I go back and read the threads about chewed up screws, gouged sideplate edges from prying, and lost springs, and I feel better about my decision!
When I feel the need to do a really thorough clean and lube, I remove the grips, and using a nozzle straw, spray gun cleaner way up into the lockwork and up behind the trigger to remove any debris or congealed lube. I do this a couple of times, cycling the action between sprays, and shake vigorously to remove any debris. I then spray some CLP into the lockwork, cycle the action several times, open the cylinder and prop the revolver upright and muzzle down to allow excess lubricant to drain.
This seems to work just fine for me, at least as far as I can see.