If anyone is serious about carrying a single action for self defense, please forget about the Hollywood crap. Spinning or twirling a SA is playing around. Likewise, fanning a SA is hard on the lock work and hard to control with serious ammunition.
And please don't bring up Bob Munden. He was a gifted man with incredible reflexes and exceptional hand to eye coordination who spent more hours than most of us have left mastering his craft. He was called a 'trick shot' because very few people could pull of half of the things he did.
If you are serious about carrying a SA you need to spend every chance you get practicing. Drawing from you intended carry position, safely manipulating the hammer as you bring it to full cock, then hitting what you're aiming at as quickly as you can rather than wasting time, ammo, and gun parts playing like a Hollywood hero.
I personally don't think reloading a SA under stress (being shot at) is a necessary skill as you will probably be taken out while your fumbling getting you ammo out one round at a time, or trying to load with 5 or 6 loose rounds in your hand. Oh, and don't forget the time it takes to empty the fired cases out of your SA. Best you be well practiced and solve the problem with your first five or six rounds.
As a retired LEO who spent my last 6 years with the department as their chief firearms instructor a cannot in good conscience recommend carrying a SA revolver as your primary self defense firearm. In my later years, because I have been a life long student of the history of the West, I own, shoot, and love single action revolvers. I shoot mine loaded with black powder, to the performance level of the original ammunition. Believe me, nobody in the old days fanned a 45 Colt with full power loads. Even if it didn't wreck your hand the chances of you hitting anything as you emptied you 5 rounds would have been a matter of pure luck. Not something to bet your life on.
Dave