I'm thinking on buying this as my next pistol.
My quetion is ; Is the grip on this pistol wide and bulky like the old .45 Model 21 pistol is ?
As mentioned already, the G20 uses the exact same frame as the G21... There is a G20SF available, though, that shortens the trigger reach for those with smaller hands. I'd definitely suggest you search out a local dealer and try them both for yourself. Those that prefer the SF models say it makes all the difference. I, myself, prefer the original grip, as I have longer fingers
Is there really a major defference between a .40 cal 180 grn. and the 10MM 200 grn. bullet ?
Yes... the differences would be a heavier bullet (~1.3grams difference based on 15.43 grains/gram) and presumably much velocity, resulting in much more kinetic energy. To use some average numbers it could break down like so:
.40cal => 180gr * 990 f/s squared, divided by 450450 = 391.64 ft/lbs
10mm => 200gr * 1150 f/s squared, divided by 450450 = 587.19 ft/lbs
10mm => 200gr * 1300 f/s squared, divided by 450450 = 750.36 ft/lbs
The 10mm loads drive a heavier projectile faster and with much more kinetic energy. This could mean more penetration, depending on the particular bullet chosen, which would make it more suitable for medium-sized game hunting or self-defense in the woods. For defense and two-legged animals I am more in favor of a lighter, medium-hot load:
10mm => 165gr * 1275 f/s squared, divided by 450450 = 595.46 ft/lbs
Just my take on it, though.
Remember, caliber choice is not so much the important thing - what *really* matters the most is how much you practice with whatever you get!
I favor 10mm, myself, but when I made that decision I also made the commitment to practice often enough to shoot it as well as I can 9mm. It took me some time to get to the point where I was happy enough with my performance that I felt comfortable carrying the G29 and, even now, I continue to practice regularly with it to maintain (and improve) my skill level.
Caliber can be a factor in how well the gun performs, but not nearly as much IMO as the shooter! Practice, practice, practice - that is the thing!