Grips for Ruger Single Six, for large hands, that won't break the bank...

I'm not sure what you mean by "standard"..but surely you are familiar with Pachmeir's presentation grips. They fully enclose the grip frame of a single six, making the grip considerably larger.
My single -six and a couple of blackhawks wear them. They look pretty good on a stainless gun too.

I think the single six takes the same grips as the blackhawk, right ? If so, I might have the perfect answer. I had a set of Badger Customs on the SBH I had. They look beautiful, and are DEFINITELY made for big hands. Price is about $80.. I'm not sure if that fits your price range, but they are well worth it my opinion. He makes them for the Single Six/BH size as well, and I assume the grip itself is the same size just a different cut. Here's the link.

http://www.badgercustomgrips.com/ruger_pistol_grips.php

I don't have the SBH anymore, but I do have 4 or 5 sets of BC grips on my S&W wheelguns. The rosewood is particularly nice.
http://www.badgercustomgrips.com/ruger_pistol_grips.php?pid=65

Here's a pic of my old SBH so you can see just how big those grips really are. They're huge, and fatter than you might expect...and that's on a big .44mag.



and the originals

Jim Badger is a great guy to deal with.

He'll custom make them to fit your hands and still charge the regular price.

Badger Custom grips are great, I have them on several of my J frame revolvers. If I had the money they would be on all my revolvers...

This guy makes grips for Ruger's that are thicker than standard and does great work.

http://www.privatescustomgrips.com/index.html