This, this is a wonderful point! The .243 is capable of clean kills further away than most folks have any business shooting at an animal. With a select few loads, I'm very comfortable on pronghorn to deer sized vitals out of the .243 at distances I would NEVER recommend to 95% of my good hunting buddies, every time we practice, the 9" plate tells them they're, on average, a 200 yard hunter. If you're not putting in the time 350 yards with any kind of a breeze on a 100 gr projectile sure is different than what you see at 100 yards.
I am super impressed that you so much better at shooting than all of your buddies!!! In the colonial days people did not have much trouble shooting deer with smooth bore muskets at 50 yards or less. When I hear of people taking shots at game from 350 to 700 yards the first thing I think is that you must be a pretty lousy hunter if you can't get any closer than that.