I know almost nothing about the .32 H&R, but I do have some experience loading sabot rounds in CZ-52 pistols and .30 Carbines. The 1/20" twist rate of the .30 Carbine makes it a hopeless case, I couldn't get it to stabilize anything, regardless of velocity. The CZ however did show some promise. I can't recall the exact rate of twist, but I think it was in the neighborhood of 1/14".
I was not able to get adequate stabilization with 50 or 52 grain bullets, but when I tried Sierra 40 gr..224 Hornet bullets they did quite well when pushed to maximum velocities with Alliant Power Pistol. H-110 gave very erratic velocities, poor accuracy and left a LOT of unburned powder behind to gum things up.
I have several CZ-52s, with bores running from .309" to .312", oddly enough, best accuracy and velocity were obtained from the .312" barreled pistol, even though the sabots miked out at .3085.
I think the 1/16" twist rate, short barrel and "jump" from cylinder to barrel are all going to prove problematic for your project, but for the best chance of success, I'd look to the shortest, lightest .224 bullet you can find, pushed by a powder that's somewhat faster burning and easier to ignite than H-110. Assuming that you're using 5.7 gr. sabots, starting loads for a 60 grain bullet should be safe. Use a very firm crimp, plastic doesn't hold near as well as gilding metal.
This is all just my opinion and probably worth less than you paid for it, as I said in the beginning, I'm totally ignorant of the .32 H&R...
Have fun and stay safe,
Swampman