I had a Dan Wesson model 15 with the 6"vent rib barrel on it.
I read about, and then worked up an Elmer Kieth load using a 125gr truncated cone and (don't load this, my memory might be off! look it up! DANGER!) 17 grains of Hercules 2400.
Cases came out fairly easily, primers not showing excess pressure, nice!
That load was supposed to do something like 1600 FPS.
It made a fireball about four feet long, and was a lot of fun to shoot.
Well, it notched the frame.
I read everything I could find on the subject, and the general opinion was that it would work harden the frame and the cutting would stop by it's self.
Being the cautious type, I continued to shoot the Elmer Kieth load and watched the frame.
True enough, the notch never got very deep at all, and never came anywhere near weakening the frame. I shot that pistol with those full house Elmer loads for about five years.
I don't know what got into me, but one day I sold that Dan Wesson to finance some other gun project and I've been kicking myself ever since. It was a truly fine piece, flame cutting and all, and I haven't seen one worth buying or I would replace it. What a fun pistol!
Don't worry about the flame cutting. It's just proof that you are not afraid of the big bullets.