To my mind, a .44spl is a superior round for SD and hunting.
Factory ammo makes this thought suspect, but if you reload, you can push a 240g cast round @ 900 ~ 1000 fps without much trouble for what EK called a "useful special" and I have to agree, they are quite useful.
Grab up an older S&W in 4", 3" if you can find one, and have at a wonderful, low recoil devastating round.
I like the .357, but I don't like supercharging a bullet to get the desired results as recoil reduces follow-up shots. In this vein, I wouldn't consider .44mag either for the purpose of SD. Too much blast and recoil.
I shoot .357 and .44mag almost exclusively, but I also load specials in these two calibers.
As was found in days of old, a large, heavy bullet doesn't need to go uber fast to get the job done, and done well.