I've got both .375 Win and .375 JDJ barrels. Neither are especially nasty, but they are sharp, and not exactly "fun" after about 5 rounds. I generally play with TrailBoss loads for fun, reserving the full power loads for special occasions. A good set of custom grips that fit your hand can take lot of the drama out of either of these. I got a set from Bullberry (I think) and spent a lot of time with the wood shop tools to make them fit my hand. YMMV.