I'm with mdi on this one. If the primers are high, I would not try to shoot them out of a semi auto. Pull the bullet, dump the powder, and then finish seating the primer or remove it and start over.
The scariest thing I've had happen while shooting was an out of battery firing. Not sure exactly how it happened, though I do know that the round was NOT a reload. Luckily for me, the gun was a Browning 1919, which is VERY robust under these circumstances. It bent the top cover and blew it open, cracked the barrel extension, and destroyed two more rounds in the feed tray. First thing I remember, before even looking at the gun, was counting for all 10 fingers.
Depending on the geometry of the bolt stripping the round off of the magazine, that high primer might be the first thing taking the impact. Having been there, I do not want to even slightly risk another OOB. In the 1919, a high primer does not present a risk because of the way the extractor and bolt interact to pull and position the round, but be that as it may, if I have a high primer, I fix it. Better safe than sorry.