The .410 BORE is more versatile, as more factory ammo is available. It is also capable of greater payloads (11/16oz, Vs. 3/4oz).
This being said, the 28 guage DOES pattern far better. Its just plain easyer to hit things. The 28 guage is a good general purpose upland cartridge. The .410 bore on the other hand, is more of an experts cartridge; you have to know your stuff to do well with it.