I don't have any first-hand experience with longer barrels for the 45 ACP but I will throw out some suggestions based on my experience with 44 Rem mag in my 9 inch Super Redhawk and 20 inch Win. 1894. Using an upper end load of Unique I find almost no difference in muzzle velocity between the two firearms. Unique is fast enough burning that the extra barrel length doesn't buy you anything in terms of muzzle velocity. But when I use an upper end load of H110 I can get over 500 fps greater MV with the Win 1894 using this slower powder. So if you're looking for improved down range performance I would suggest the following. Using a 200 or 230 gr. jacketed bullet, try working up a optimal load using a slower powder.
I would suggest one of the following powders; Win WSF (the fastest burning of the group), Viht N-350 (the most expensive of the group), HS-7 (which I understand is being discontinued), or AA No. 7 (the slowest burning of the group). The heavier bullet will likely give a clean, more complete burn in the longer barrel. Provided you have a tight, complete chamber coverage of the cartridge and your firearm is in good shape you should be safe with these powders at the upper end of the loading range for a pistol. For a 230 grain bullet the Speer manual has the following loads: N-350 - 6.3 to 7.1 gr, HS-7 - 8.5 to 9.5 gr., and AA #7 - 8.6 to 9.6 gr. Carefully work your way up and keep an dilligent eye out for signs of over pressure.
I hesitate to say the following but I have seen 45 ACP rifle loads with a 200 gr. bullet using as much as 12 gr. of AA #7, 7.9 gr. Viht N-350, and 7.3 gr. WSF. For the 230 gr. bullet 11 gr. AA #7, 7.6 gr. Viht N-350, 10 gr. HS-7, and 7.0 gr. WSF. Do not start at these loads. Also, I have no information on the external ballistics of these loads. Remember you are limited by both the strength of the chamber/barrel and the 45 ACP case. The 45 ACP case is not all that strong!