i know this thread is a tad old, but i just had to, not many 480 threads out there. I have a SRH in Ruger 480 and a Puma M92 in Ruger 480. I love them both. This fall i got a Elk Cow at 70 yds with the puma using iron sights. For the Elk i used a Hornady 325gr XTP and dropped the cow with one shot. I'm working on a load to hunt with the pistol this coming fall.
If you reload it isn't that expensive, primers are large pistol, power (tons to choose from) and bullets you can use Ruger 480 or Linbaugh (same .475 bullet)so there are also several to choose from. The velocity is low enough you can easily cast with Wheel weights and have great bullets, again lots of molds out there to choose from. The only thing is the brass. I just keep an eye out for them on clearance and get a box here and there. But once you have 200-300 rounds do you really need more? Being a revolver you don't loose that much, and lever action it might loose more but not that bad. Worst case you could buy some linebaugh brass and shave some off.
I love the round and I'm proud to shoot it, every time I'm at the range someone always wants to shoot it, so usually load 2-3 extra rounds just to educate other revolver lovers in my area. sure there are more "powerful" rounds and there always will be no matter what you have, the question is, does it do what you need it to? for me the 480 does it, and I have fun doing it. what else is there?