I've been working a lot lately with the .260Rem. (very close to the Swede). I've found that with RL22, that I can't get decent velocities with bullets 140gr or lighter.
I'm getting best performance with IMR4350. With a 140, I get best accuracy at ~2,650fps with a 140gr bullet, and 120gr bullets at 2,900fps (20"bbl Rem. M7).
However, with the Sierra 160gr RN, 43.0gr of RL22 gives 2,430fps and 1-moa or better groups (5-shots). 44.0 is too hot, (cratered primers and burnished case heads), but was near one-hole accuracy at 2,470fps.
I had just a tad of RL19 left from an older lot#. It never was good in anything I tried it in. I did get 3,000fps from a 120gr bullet, but accuracy was over 3". Same bullet with 44.0gr of RL17 gives .5moa-5shots at 2,850fps or 42.0gr of IMR4350 for 2,650fps for near 1-hole groups (too slow for my purposes).
The individual lot# of powder can make a huge difference with some powders. I suspect that Varget is one of them... The Varget I've used neither gave me the accuracy or velocities claimed.....