Copying and pasting what I posted in an old thread on the same topic...
I have been substituting small rifle magnum(SRM) in place of small pistol primers(SPP) for years with no adverse effects. Some pistols don't have enough force on the hammer or striker to set off SRMs, but I have had no issue with any of mine thus far. Just for kicks, I ran some loads past my chronograph while doing other testing the other day.
Load was as follows:
124gr Hornady FMJ
5.0gr unique
Once fired(honestly only fired one time) Remington brass
Fiocchi SRM or SPP
Fired from a polymer80 "glock 19" build
SRM Results
1174
1175
1167
1172
1149
Average: 1167.28fps
SPP Results
1155
1164
1189
1169
1159
Average: 1167.14fps
Overall difference between the two of 0.14 feet per second. Granted, this wasn't a giant sample, but I feel they are close enough that I don't have any concerns as to substituting.
Having said that, I WILL NOT substitute SPP in place of SRM, as the SPP has a thinner cup and I would be afraid of primers getting pierced or failing at the higher pressures.