They do indeed, but without question they push the limit. The problem with Colt Detective Specials is that when pushed they sometimes go out of time and won't "carry up" (fully revolve the cylinder from one chamber to the next). This is not hard to correct, and if done before the condition gets to bad does't require new parts. However doing the tuning requires specialized knowledge and experience. Now 'smiths with those qualifications are disappearing, as are new parts. Used parts that were hand-fitted to another revolver may not work in a different gun. Unlike many of today's revolvers (and pistols for that matter) these Colt revolvers that were originally introduced in or around 1908 were not designed or assembled on a drop-the-parts-in basis.
This is not to say that they are fragile, which they are not, but to point out that they were not made to use some of today's hotter loads
on a substantial basis unless you can do what was formally recommended before World War Two. Mail the gun into the factory once a year (more or less depending how much it's used) have a quick tune-up done for free, and then sent back in a week or so to your mailbox. That was then and this is now.
My middle-1950's Detective Special is usually loaded with 148 grain mid-range wad-cutters when used for general plink & play shooting, and also for inside home defense based on over penetration issues. Otherwise with 158 grain semi-wadcutters. I don't worry about hollow points. If, on infrequent occasions I think I need more I have a Taurus 445 snubby chambered in .44 Special and other .38 Special/.357 Magnums with 4" or longer barrels.
My Dective Special is finish worn, but as tight as the day it came out of the factory, and it has no timing problems what-so-ever.