There are so many variables in shooting sub-MOA groups that this post could end up as a book, from neck turning to bullet swaging to adjustable triggers to powder measures to bullet placement in the case, etc...... All will have some effect, but the question of are they worth it? That only you can answer.
If you are a National Championship shooter and get sponsorships worth 100 of thousands of dollars the answer would be yes, otherwise a maybe or no would be more approprate.
As a matter of fact there are 100s of books out on accuracy tuning your loads and rifle, it might not hurt to get one or two of them.
What I find in my reloads is this:
1. Make sure each and every charge of powder is EXACTLY the same right down to the 1/10 of a grain. (Trickle charge or use a electronic dispenser/scale combination)
2. Use a L-N-L OAL gauge to find your Max OAL for the rifle bullet combination and then back off that by 0.050 inches.
3. Full length resize all your cases using a case gauge to eleminate any headspace gaps.
4. Get a trigger job for the rifle or use an adjustable trigger with no creep set to the lowest SAFE trigger pull (1lbs or less).
5. Make sure each bullet is set in the case straight and is not canted.
6. Test your loads on your rifle and find the best balance (of power and bullet weight) for your barrels harmonics.
7. Take your time on each shot don't rush them.
8. Shoot on calm days with very little wind.
All the rest of the work is at your discression and may or may not help.
Jim
5 shot group, and yes you will have fliers but that's you not the load or rifle.