I used to use a revolver in Centerfire many years ago, but I got a Smith 52 in 1987, and I've been using that ever since.
Recently, I got an old Officers Model to use for the Distinguished Revolver matches, so I'll be shooting a little bullseye w/revolver soon.
Your choices are a 38 revolver for centerfire, or a 45 ACP revolver for both CF and 45. Don't mess with 45 Long Colt. With the ACP, you can use moon clips preloaded the night before. Also, you could use a 22 revolver in the 22 portion.
The main thing is you need to be able to cock the gun one-handed, aim, shoot, and repeat. 5 times in 10 seconds.
Good luck!