For driven/stalking/moving hunts, definitely. Then again, for treestand/blind in open terrain they're IMO an ideal combination of accuracy, range, recoil management and repeat shot(s) if need be. Or simply shooting three deer in one pile when you still have bunch of tags on the last day of the season when sun starts to set. I haven't kept track of how many have fallen to mine over the years but I'd give it quite a bit of credit for keeping my freezers stocked.IMHO, once you get to AR10's, the rifles are just too heavy to fool with for hunting.
I've carried other rifles lately, mainly because most hunts have been driven and had a dress code which AR:s don't really fit in, but tomorrow is another treestand evening and I'll take the .308 AR. Mainly because the stand is just a 100yd hike from the nearest road, I wouldn't like carrying all its bulk much further.