The science of wound ballistics is fascinating, and I've spent more than 20 years studying it. The bullets today are better than they've ever been. .45 ball's reputation is a little overrated, much of it based on folklore. As has been said here before, .45 ball's ability to penetrate, combined with it's diameter, are why it's a better choice than the smaller FMJ rounds. Good hollow point designs offer advantages such as, larger wound channel, less over penetration, and a better cutting effect, which will cause more bleeding.
What you
don't want, is one of the whiz bang, hyper velocity, lightweight, frangible bullets the snake oil salesman have been pushing since the 60's, and continue to push today.
Interesting though, that the late Gene Wolberg, IMHO, the finest wound ballistics expert of the late 20th century, used words almost identical to Old Fuff's.
Old Fuff said:
Anyway I pay far more attention to bullet placement that what the size or shape of it is. The first rule is, and will always be ...
Hit the target !!!
BTW, it was five years ago this last weekend that Gene Wolberg died. Gene did much of the work for the more well known wound ballistics experts, but never did the self promotion work to make himself famous. He was a quiet genius, that we all owe a debt of gratitude to. I hope where he's at, he has a heck of a range, and lots of weird calibers to work up loads for.