Velocity is not a good indicator of pressure. A given velocity that is safe with one powder in one gun may not be safe in another gun, and if you change powder, the previously safe velocity load could become a dangerously overpressured load.
Best way to determine if you are getting close to 'dangerous pressure land' is to guy a good micrometer and measure the casehead diameter before firing and after firing. If the case head expands by .0005" or more, you need to back your loads down.