33 grains of imr 3031 works great excellant accuracy, ive been using this load in my rem 700 bdl hv bbl rifle for the past 20 yrs or so , on woodchucks, coyotes , with great results with all 50 & 55 gr bullets expecially v max or any other brands so it should be good for the varmint granades also, another great powder for the 22/250 is imr 4064 & H 380