I don't think there is a "comfortable" handgun to hunt/defend yourself against bear. Ouch! Most important thing is you hit the target. Never hunted nor defended myself against bear. Never even shot at a bear silhouette. Get the biggest caliber handgun you can shoot and practice, practice, practice.
You are defending yourself because you didn't see the bear at a distance. He's in your face. Lord help you if he is a she w/cubs.
PB