Well...yes and no.
That 146 is jacketed where the bullet rubs against the barrel on it's way out, but exposed lead past that. The good news is that at speeds above 1,000fps, there's no barrel leading.
The bad news is twofold: first, lead being slicker than copper, the 146 will tend to move about as fast for the same pressure as a 158 plain lead.
Second, I'd think it needs just a BIT more speed than the 158 to fully expand (to get the jacketed area to stretch out), although I doubt the difference is significant. The 158 plain lead is effective at around 850fps and generally gets there even out of a 2" barrel in factory loads, unless it's a wimpy Federal
. You could drive the 146 at that speed but...why? You're down a bit on peak energy due to the bullet weight difference and plain lead won't gunk up the barrel very badly below 900 - 1,000fps.
If you have a very strong 38Spl gun or a 357, then you're in good shape - get the 146 cookin' along at about 1,050 - 1,150fps and yes, works great. Neatly bridges the gap between full-on 357 and 38+P.
But you're over SAAMI spec for 38+P at that point, and if the gun isn't a really beefy critter, you better understand your pressure curves with your powder type REAL well or you'll spike into the red. UNLESS you've got a 38Spl gun with a 6" barrel and get your speed that way - I'm thinking mainly of those folks with 2" - 3" barrels and marginal rating for +P at best.
On the other hand, if you're going to run down below 950 - 1,000fps, you might as well just stay with the 158 lead classic.
Upshot: I see that 146 as the foundation for a nice "mellow but effective" 357 "lite", versus hotrodding the 38+P...at least for most applications. (It would ROCK as a 38Spl rifle load but how common are those?)