Unique for me
I have always used Unique, guess that's what my friend was using when he introduced me to reloading many, many years ago.
I've tried other "pistol" powders, when I couldn't find any loading data for Unique, but always went back to Unique.
As with any powder, IMO, you want one that fills up as much of the case as possible, so you can't "double charge" the round. Also one that burns clean, has loading data for everything you want to load.
Unique fills the bill!!
I use it for 380, 9mm, 40 S$W, 38 & .357, 45 LC, 45 ACP and .410 & 12 ga.
just my .02 cents worth