Boat tails unless "bonded cored" are also more apt to shed their jackets then flat base. Flat base designs are also usually more accurate at shorter range then the BT.
I have seen respected gun writers claim that boat tails come apart on game, and that they don't -- and both back it up with statistical accounts of many head of game shot with both boat tails and flat bases.
My own experience and that of a few of my friends is that boat tails DO tend to come apart in game. I once shot a running white tail with a .30-06, he went down and came back up, went down at the second shot, bounced up again, and it took a third shot to put him down permanently.
The first shot was a perfect quartering away shot from the right. The bullet struck the deer in the flank, angled forward, and came apart. I found the jacket lodged against the leg bone -- it should have broken that bone.
The second shot was a mirror image, but this time the deer was quartering the other way. Again, the bullet angled forward, and the jacket was found lodged against the opposite leg bone. The third shot was broadside, and the bullet was not recovered.
A friend had an almost identical experience on a 450-lb black bear, which he finished off with a .357.
Also, the base of the bullet is the most critical part for accuracy -- you can deliberately deform bullet noses and shoot good groups. But mess with the base, and kiss accuracy good bye. A good flat base will therefore be more accurate than a medeocre boat tail.
For a hunter, the only advantage of a boat tail that I see is that they are easier to hand load -- the boat tail allows you to seat them firmly in the case by hand before you run them up into the seating die.