Like my Buck Mark
Can't speak to the merits of the Ruger .22s.
However, one of my first two handguns is a Buck Mark (Browning spells it as two words) -- specifically, a Buck Mark Plus. The Plus is a BM Standard with a high-visibility front sight and nice rosewood grips. Cost me $350.
I really like it. For a casual sporting pistol with a mid-length barrel, it is crazy accurate. I can get 2" groups offhand at 40 feet or so, despite primitive skills. A 5'3" relative of mine particularly likes the Buck Mark for its balance, gentle recoil and moderate weight (2 lbs., 2 oz.).
I've put 350-400 rounds through the Buck Mark. It is due for its first full takedown and cleaning. However, it has kept on shooting with virtually no problems. It seems to like CCI Mini-Mags.
My gun has one quirk: when you chamber the first round, the orthodox pistol slide-racking technique (pull the slide smartly back, then simply release it, letting the spring tension do all the work of snapping the slide into place and chambering the round) doesn't always work. My amateur hypothesis is that this is because the slide springs on a .22 pistol cannot be made too stiff -- otherwise the modest blowback force of the cartridge will not suffice to push the slide back and feed the next round.
My solution is to give the slide a slight forward push when chambering the first round. Once I learned to do that, I've had 200+ rounds without a burp or misfeed.
Shooting the Buck Mark is so relaxing that I plan to buy another .22. I'm leaning toward a Ruger New Single Six revolver.