Howdy
First off, slugging the bore is easy. I do it all the time. If you want my instructions on how to slug a barrel send me a PM and I will be glad to send it to you.
Up until WWII the standard groove diameter for 45 Colt was .454. That's what .454 diameter bullets are really for. When the SAA was reintroduced after WWII (actually in the mid 1950s) 45 Colt groove diameter was changed to .451 so it would be the same as 45 ACP.
Pretty much, most modern manufacturers are pretty good at keeping their 45 Colt barrels to .451.
Chamber throats are a whole 'nother story. They can vary all over the place. I have a couple of 2nd Gen Colts with chamber throats around .455.
Ideally, chamber throat diameter will be the same diameter, or slightly larger than rifling groove diameter. You don't want much space around the bullet as it goes through the chamber throat, or hot gasses can squirt around the bullet and soften it as it goes through the chamber throat, a major cause of leading. You want a nice tight fit as the bullet goes through the chamber throat. Of course, we are stuck with whatever groove diameter the barrel has. If chamber throats are too tight, the bullet can be squeezed down as it goes through the throat, and then might not engage the rifling properly. Tight chamber throats can be opened up. But you have to live with chamber throats that are too big. The best you can do is choose a bullet that fits the oversized chamber throat pretty well, then have it be sized down as it passes through the forcing cone. But too much squeezing down is not good either.
Your revolver will tell you what diameter bullets it wants. Simply remove the cylinder and point it at the ground. Get ahold of some .452 bullets and some .454 bullets. Drop a bullet into a chamber. What happens? If the bullet drops right through, it is too small. If it hangs up and requires a gentle shove with a pencil to push it through, it is perfect. If it hangs up and requires a lot of force to shove it through the chamber throat, it is too big. Pretty simple. Try this test with both .452 and .454 bullets, be sure to try it in several chambers. The cylinder will tell you what diameter bullets it wants.