Even though it is a big press I don't think it could full length resize a 50 BMG. The linkage is a simple toggle linkage not a compound linkage found on modern presses. Fred Hunington of RCBS fame held the patent on the compound linkage and it was valid to the late 60's. Loading rifle cases on older simple toggle linkage presses pretty much sucked. However they worked well on straight wall handgun cartridges. The Coax press was actually a work around of the Hunington patent.
It's a double linkage press, it's just the picture.
Those holes in the turret are for 1-1/2" 50 BMG dies. They also sold thread reducers for smaller dies.
Here's a different Hollywood press that has both large and small diameter holes.
This one uses a single linkage and I wouldn't consider it for 50 BMG.