Most of my guns are for entertainment and hunting. Home security was kind of an afterthought, but we did finally provide for that.
A large dog, one of the protective breeds, is a lot of security. Daughter has a German Shepherd who is VERY protective of her and her family. I'm sure he would take a chunk out of anyone not welcome in their home.
A couple of pepper sprays are a good thing to stash. I usually have one unobtrusively hanging to one side of my front door. They are small, non-lethal, and inexpensive. I'm told that someone who catches a face full of that stuff will be pretty much incapacitated for at least half an hour. Of course, if you spray, you're likely to catch a bit of it yourself.
A very bright flashlight, with a pulse feature, is very important to have.
Now, if my pants are on, my little 380 is on my belt, unless I'm headed for the Post Office. What I've been taught is that in a pinch, you often have very little time to respond. We have a little safe near the foot of our bed, and that's where the carry guns go at night, with the door open. When we have visitors or are away, the door is closed and the magazine from my M4gery joins the handguns in the safe.