I've been loading my own rifle ammo for about the last 15 years, 22Hornet, .204, and 223, all using the same small rifle primers. Through the years I've used mostly Remington 7.5 BR and some CCI but have Winchester and Federal in my stash that I've never used. I just buy whatever I've found bargains on at gun shows and. stash them for later use. But, since I've been able to buy the Rem and CCI, that's what I use. I never thought to ask if there are differences I should be aware of. While I'm not a bench rest shooter, I do shoot a lot of prairie dogs at fairly long ranges up to about 300+ yds so accuracy is important to me. And when I test fire rifles and hand loads, I won't tolerate a rifle or ammo that will not perform. So are their differences it would help to be aware of?