No problems using the 650 and 223/5.56. Some stick powder pieces will crunch with the Dillon power dispenser, but I use quick-measure.com on my station 2 and it works amazingly well with all powders- no waiting for all the powder to drop. I'm glad I have it, but I don't find that I actually need it. I think it's more beneficial for folks that want very consistent charges (+\- 0.1gr). I honestly don't care if my charges vary up to half a grain for my purposes. I can't tell a difference at least when l I load with a wider charging tolerance vs obsessively replicating the same charge for every round.