There are several good calibers out ther so everyone has the opertunity to pick ther faveret for me it comes down to range and your own ability.
For brush you can't beat a good brush gun 30-30,35 Remington,44 magnum.
For a litle more open country the 243,260,308,7-30 waters,6.5x55.
For something that you need to reach out farther 30-06,280,270,25-06,300 mag.
It's hard to beat the old 30-06 with all the bullets to choose from you can go from 2300 fps to almost 3000fps I think that one is hard to beat.
Flip