Folks who carry the 44spl seem to love it. How'd you compare it to the 45acp for self defense - given a 6-shot revolver in either case?
For me, that's a silly comparison, platform-wise.
I suppose you could ream the chambers of the .45 acp to accept the .460 Rowland, but if I wantedore power, I'd just take a .45 Colt or .44 magnum instead.
So that leaves me to compare standard ACP ammo to the .44 Special. My first question would be, what will the Special do the ACP won't? If the ACP is loaded with a 230 grain bullet @ 950 fps and the Special has a 240 @ 950 fps, I'm going to carry the ACP in a 1911. I'll have a gun that's lighter, flatter, easier to carry/conceal that holds more rounds that's easier and faster to reload.
The revolver needs to do something for me that the 1911 won't. Bump those loads up to 1050-1100fps, then I'd go with the Special.
If you insist I choose between an ACP and Special revolver, I'd choose the Ruger 4 5/8ths" .44 Special (if I had one) over my heavier five inch 625, even tho moonclips allow for a faster reload.
Ok, I just re-read the OP. I'm still in "Trail Gun" mode from another thread!
For strictly defensive purposes, I'd go with the .45 ACP.